What’s grape seed extract? Do you know the advantages of grape seed extract?

What’s grape seed extract? Do you know the advantages of grape seed extract?

MNT Knowledge Center

Grape seed extract is definitely an industrial derivative of grape seeds, very wealthy in antioxidants and oligomeric proanthocyanidin complexes (OPCs).

The extract continues to be associated with an array of possible therapeutic qualities including healing wounds and treating conditions for example high cholesterol levels, coronary artery disease, macular degeneration, poor circulation, nerve damage, in addition to stopping cancer.

Although a number of these health claims continue to be not completely maintained by “top qualityInch studies, strong evidence is starting to emerge on grape seed extract’s extensive health advantages.

Grape seed extract can be obtained like a nutritional supplement either in a liquid form, tablets or capsules. Supplements generally contain between fifty to one hundred mg from the extract.

This Medical News Today information article provides information on the advantages of grape seed extract in addition to negative effects and safeguards connected using its use.

Do you know the advantages of grape seed extract

Grape seeds are associated with numerous

health advantages

Studies on animal designs include says the extract could be good at treating heart illnesses. Some experts believe that grape seed extract may even have anticancer and cancer chemopreventive potential.

Over the past few years there’s been a lot of research pointing to key therapeutic qualities from the grape seed extract. The following are the key findings.

Health advantages connected with grape seed extract:

    • Healing wounds – Grape seed extract can heal dermal wounds.

      A study, published in the journal Free Radical Biology and Medicine1, “provided firm evidence to support that topical application of GSPE represents a feasible and productive approach to support dermal wound healing.”


    • Improving bone strength – Including grape seed extract in your diet with calcium has a “beneficial effect on bone formation and bone strength for the treatment of bone debility caused by a low level of calcium,” according to research published in the Journal of Musculoskeletal & Neuronal Interactions.2


    • Preventing skin cancer – Grape seeds contain proanthocyanidins which can prevent the development of cancer.

      A study, published in the journal Molecular Nutrition & Food Research3, found that grape seeds have properties that can reduce the severity of skin cancer. The researchers concluded that grape seed extracts “could be useful in the attenuation of the adverse UV-induced health effects in human skin.”


    • Cardiovascular benefits – The antioxidants in grape seed extract can potentially protect the blood vessels from becoming damaged, which may prevent high blood pressure.

      According to one study, published in the journal Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis4, “grape seed proanthocyanidin extract (GSPE) provides superior antioxidant efficacy as compared to Vitamins C, E and β-carotene.”


    • Reducing edema (swelling) – Taking grape seed extract can help reduce the swelling that occurs after an injury or surgery.

      A double-blind, placebo-controlled study found that breast cancer patients who took 600 mg of grape seed extract every day for 6 months had less edema compared to those on placebo.


  • Preventing cognitive decline – Grape seed extract is very high in proanthocyanidins (oligomers of monomeric polyphenols) which may prevent cognitive decline.

    One study identified “a critical role for grape seed proanthocyanidin extract (GSPE) as a neuroprotectant in the hippocampus and in preventing cognitive loss with aging.”5

Video – Dr. John Gray talks about the possibility of using grape seed extract to reduce symptoms of ADHD.


Other potential benefits associated with grape seed extract:6

  • Treating tooth decay7
  • Protecting against pathogens
  • Improving night vision
  • Alzheimer’s disease
  • Treating diabetic retinopathy and improving blood sugar control
  • Relieving symptoms of chronic venous insufficiency
  • Anti-aging properties (protecting collagen and elastin)

Negative effects and safeguards

Common negative effects include:

  • Headache
  • Sore throat
  • Dizziness
  • Itchy scalp
  • Stomach ache
  • Nausea

You should speak to your physician before you take grape seed extract as it can certainly affect the way in which certain medications are damaged lower within the liver.

It’s possible that grape seed extract can behave as a bloodstream-thinner, which increases the chance of bleeding if taken together with anticoagulants for example warfarin or aspirin. Based on RxList8, “Taking grape seed together with warfarin (Coumadin) might increase the likelihood of bruising and bleeding.”

Additionally, women that are pregnant should completely avoid taking grape seed extract supplements.


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